Advice for mothers using Acetaminophen while breastfeeding. Includes possible effects on breastfed infants and lactation. Jan 18, What To Do When You Have Sinus Pain by Allison Ishman and Tylenol ( Acetaminophen) are considered compatible with breastfeeding. Safe-to-take medication for common ailments while you're breastfeeding. cough; acetaminophen (Tylenol) or ibuprofen (Advil or Motrin) for body aches. What can I drink to treat a cold while I'm breastfeeding? Can I take Acetaminophen while breastfeeding? Acetaminophen is a good choice for analgesia, and fever reduction in nursing mothers. Amounts in milk are . Jan 26, Is ibuprofen (Aleve, Motrin) safe to take while breastfeeding? How about acetaminophen (Tylenol) or naproxen (Aleve)?. Mar 6, Taking Tylenol When Breastfeeding. Yes, it is considered safe to take Tylenol when you are breastfeeding. A small amount of this medication.